Polycyclic aromatic hydrocarbon

Indeno[1,2,3-cd]pyrene in the bedroom

Indeno[1,2,3-cd]pyrene is a five-ring PAH classified by IARC as Group 2B (possibly carcinogenic to humans, Monographs Vol. 92, 2010). It is one of the 8 PAHs restricted in consumer articles under EU REACH Annex XVII Entry 50. As a high-molecular-weight PAH, it is predominantly particle-bound rather than volatile — meaning it associates with particulate matter in air and dust rather than existing as a free vapour. In the bedroom, indeno[1,2,3-cd]pyrene is found in combustion-derived dust from diesel exhaust, tobacco smoke, and wood burning.

Indeno[1,2,3-cd]pyrene — Embr Bedroom Chemistry Atlas

At a glance

Chemical familyPolycyclic aromatic hydrocarbon (PAH) — five-ring high-molecular-weight structure
CAS number193-39-5
ClassificationIARC Group 2B (possibly carcinogenic to humans, Monographs Vol. 92, 2010). EU CLP Carc. 1B (H350). One of the 8 EU REACH Entry 50 restricted PAHs
Where you encounter itDiesel exhaust; tobacco smoke; coal and wood combustion; coal tar; predominantly particle-bound in air; household dust from combustion sources
Sleep micro-environment relevanceFound in household dust as a particle-bound PAH from combustion sources. Less volatile than lighter PAHs — exposure is primarily through dust particles rather than air. Contributes to cumulative PAH cancer risk

Regulatory & certification status

European UnionCLP Carc. 1B (H350). REACH Annex XVII Entry 50 restricts 8 priority PAHs (including IcdP) to 1 mg/kg in rubber and plastic components with prolonged skin contact. Regulatory
United StatesEPA Priority Pollutant. Clean Water Act listed. Not specifically restricted in consumer products beyond ambient criteria. Regulatory
CanadaCEPA Schedule 1 (toxic substance) as part of the PAH group. Regulatory
InternationalIARC Group 2B (possibly carcinogenic, Monographs Vol. 92, 2010). One of the 8 EU priority PAHs restricted in consumer articles. Regulatory

What it is

Indeno[1,2,3-cd]pyrene (IcdP) is a five-ring PAH with a molecular weight of 276 g/mol. Its high molecular weight means it is almost entirely associated with particulate matter in the environment — it does not exist as a free vapour under ambient conditions. IARC classified IcdP as Group 2B in Monographs Vol. 92 based on sufficient evidence of carcinogenicity in animals and inadequate evidence in humans. The EU classifies it as Carc. 1B under CLP. IcdP is produced during incomplete combustion and is found in diesel exhaust, tobacco smoke, coal tar, and wood smoke. It is commonly measured as part of the EPA priority PAH panel and the EU Entry 50 restricted PAH group.

Where it shows up in bedding

Indeno[1,2,3-cd]pyrene is not used in bedding products. It enters bedrooms bound to particulate matter from combustion sources: diesel exhaust from outdoor traffic that infiltrates indoors, tobacco smoke residue on surfaces and in dust, and fireplace or wood stove emissions. Because IcdP is particle-bound, it accumulates in settled dust rather than remaining airborne. During sleep, exposure occurs primarily through ingestion and dermal contact with contaminated dust, rather than inhalation of vapours. Regular cleaning to reduce dust accumulation is the most effective way to reduce exposure.

Citations

  1. IARC (2010). Some Non-Heterocyclic Polycyclic Aromatic Hydrocarbons. IARC Monographs Vol. 92. Source Peer-reviewed
  2. ATSDR (1995). Toxicological Profile for Polycyclic Aromatic Hydrocarbons (PAHs). Source Regulatory
  3. EU REACH Annex XVII, Entry 50 — PAHs in consumer articles. Source Regulatory

Frequently asked questions

  • Why is indeno[1,2,3-cd]pyrene particle-bound?

    Its high molecular weight (276 g/mol) and low vapour pressure mean it does not evaporate into the air at ambient temperatures. Instead, it adsorbs onto the surface of particulate matter — soot, dust, and other fine particles generated during combustion. This means exposure is primarily through contact with or ingestion of contaminated particles rather than breathing vapours.

  • Is indeno[1,2,3-cd]pyrene in my mattress?

    No. IcdP is not a mattress material. If it is present in your bedroom, it comes from combustion-derived dust — outdoor diesel exhaust that infiltrates through windows, tobacco smoke residue, or fireplace/wood stove emissions. Reducing these sources and regular dust cleaning are the most effective controls.

Related compounds


Embr is a sleep environment company researching and addressing the chemistry of the bedroom. Research and product development in progress.

Last reviewed 2026-07-08. If you find a factual error, contact us.