At a glance
| Chemical family | An organic UV filter (absorbs UVB and short UVA); also stabilises the UVA filter avobenzone |
| CAS number | 6197-30-4 |
| Classification | EU SCCS: safe as a UV filter up to 10% in cosmetics. Low skin absorption; not genotoxic; endocrine evidence not conclusive. Its degradation product benzophenone is a separate, higher concern |
| Where you encounter it | Sunscreens, day creams, lip products and other cosmetics. The bedroom route is transfer from skin-applied product onto bedding |
| Sleep micro-environment relevance | A leave-on personal-care residue rather than a mattress ingredient; the notable issue is benzophenone formed as the product ages, not the octocrylene itself |
| Activated carbon capture | Not the lever — product choice (avoid old product; octocrylene-free or mineral sunscreens) and ordinary laundering address it |
Regulatory & certification status
Where Octocrylene stands across the major regulatory systems and the certifications a bedroom product might carry. Each row links to the governing instrument; where a jurisdiction has no specific measure, that is stated plainly rather than left blank.
| European Union | Octocrylene (EC 228-250-8) has NO harmonised CLP classification in Annex VI of Regulation (EC) 1272/2008; registrants self-classify. It is not on the REACH SVHC Candidate List, the Authorisation List (Annex XIV), or the Restriction list (Annex XVII). It is the subject of an ECHA substance evaluation (assessed by France for persistence/bioaccumulation/toxicity and suspected endocrine-disruptor concerns). Following an ANSES proposal, ECHA opened a public consultation (24 Sep 2025 - 24 Mar 2026) on a PROPOSED REACH restriction that would prohibit placing on the market or use of finished cosmetic products containing octocrylene at a concentration >=0.001% w/w, on environmental (aquatic) grounds; RAC/SEAC opinions are expected around September 2026 and any restriction would apply 24 months after entry into force. As of mid-2026 this is a draft proposal and not in force. Under the Cosmetics Regulation (EC) 1223/2009 octocrylene remains an authorised UV filter (Annex VI entry 10, maximum 10%, with a lower sub-limit for some propellant sprays). Regulatory — ANSES · ECHA |
| United States | Octocrylene is NOT on the California Proposition 65 list (checked against the current OEHHA list, version dated 5 December 2025 - no entry for octocrylene under cancer, developmental, or reproductive endpoints). It is not subject to a TSCA risk evaluation, prioritisation, or work-plan action by EPA; in the US it is principally an OTC sunscreen active regulated by the FDA under the sunscreen monograph rather than via TSCA industrial-chemical action. (Note: benzophenone, a degradation/impurity product of octocrylene, IS a separate Proposition 65-listed chemical, but octocrylene itself is not.) Regulatory — OEHHA · US EPA |
| Canada | Octocrylene is not listed on CEPA Schedule 1 (Toxic Substances) and is not the subject of a final Chemicals Management Plan toxic determination. In Canada it is regulated chiefly as a permitted UV-filter sunscreen active: it is named as an acceptable sunscreen active ingredient in Health Canada's Sunscreen Monograph (administered by the NNHPD; sunscreens with chemical UV filters are non-prescription drugs requiring a DIN), allowed up to roughly 10%. It is not independently confirmed to appear as a named prohibited or restricted entry on the Cosmetic Ingredient Hotlist, so no specific cosmetic prohibition beyond the standard sunscreen-active framework is identified. Regulatory — Health Canada · Government of Canada |
| Australia | AICIS evaluated octocrylene's industrial (cosmetic) uses under evaluation EVA00182. The draft evaluation statement was published 31 March 2025 and, after public consultation (closed 29 May 2025), the evaluation was finalised and listed in AICIS's Notice of completed evaluations dated 26 June 2025 - so this is now a completed evaluation, not merely a draft. Contrary to a 'no risk' reading, the evaluation identified a POTENTIAL human-health concern: based on an extended one-generation reproductive toxicity study (EOGRTS), the chemical may cause adverse effects on fertility (a reduced number of implantation sites and fewer pups delivered), observed at high doses alongside mild maternal toxicity; no specific developmental effects were seen, and the assessment notes that benzophenone (a breakdown product/impurity) has evidence of carcinogenicity in animals. The evaluation covers industrial/cosmetic uses; therapeutic-sunscreen use is regulated separately by the TGA. AICIS imposes no new binding cosmetic restriction itself. Regulatory — AICIS |
| United Kingdom | Under GB CLP there is no mandatory (harmonised) human-health classification for octocrylene, and under UK REACH it carries no restriction. The UK Scientific Advisory Group on Chemical Safety (SAG-CS) Final Opinion on octocrylene (published 24 October 2024) concluded it is safe for use as a UV filter at up to 10% (used individually or in combination), judged the evidence for endocrine disruption weak/inconclusive (octocrylene unlikely to be an endocrine disruptor on the WHO definition), and recommended a fuller risk assessment in children and adolescents once adequate data and methodology exist. It remains an authorised UV filter under the GB Cosmetics Regulation (Annex VI entry 10, max 10%). Regulatory — UK SAG-CS · UK legislation |
| Certifications | None of these certifications specifically name octocrylene, which is a cosmetic/sunscreen UV filter rather than a foam or textile additive. CertiPUR-US: not applicable - it certifies polyurethane foam content/emissions and its published criteria do not cover cosmetic UV filters. OEKO-TEX Standard 100: octocrylene is not identified as a named regulated parameter in its textile limit-value list; its scope is textile content limits, not cosmetic actives. GREENGUARD / GREENGUARD Gold: a low-VOC chemical-emissions certification for products and furnishings that does not screen for a non-volatile cosmetic ingredient like this. In short, octocrylene falls outside the scope of all three programmes. Industry — CertiPUR-US · OEKO-TEX |
| The 72-hour test window | Largely missed. Octocrylene is a non-volatile SVOC (very low vapour pressure, MW ~361, lipophilic and environmentally persistent) that migrates onto skin and into house dust rather than off-gassing, so a short ~72-hour VOC chamber emissions test does not reliably capture it. Inferred — from the compound's volatility/emission profile versus the VOC focus of short chamber tests |
What it is
Octocrylene is a chemical sunscreen ingredient — an organic UV filter that absorbs UVB and short-UVA light, and a useful one, because it also stabilises avobenzone, the main UVA filter, which otherwise breaks down in sunlight. It is found in a large share of sunscreens, day creams and cosmetics. On its own merits, the safety verdict is favourable: the EU Scientific Committee on Consumer Safety judged octocrylene safe as a UV filter up to 10% in cosmetics (and up to 9% in sunscreen propellant sprays for combined use). Regulatory — EU SCCS Opinion SCCS/1627/21
A comprehensive toxicology review reinforces that: octocrylene shows very low percutaneous absorption — about 0.33% of an applied dose — is not genotoxic, shows no androgenic, estrogenic or thyroid effects, and yields margins of safety above 100, supporting its safe use up to 10%. Peer-reviewed — Norman et al. 2025 The endocrine-disruption concern that triggered the EU re-evaluation was examined and judged not conclusive enough to act on. Regulatory — EU SCCS If the story ended there, octocrylene would be a quiet, low-concern entry.
How it relates to the bedroom
A skin-applied residue, not a mattress chemical
Octocrylene reaches the bedroom the way the rest of the personal-care family does: applied to skin in a sunscreen or day cream, it is a leave-on product that transfers onto the bedding you then lie on. Inferred — leave-on skin products transfer onto bedding, as documented for other personal-care residues Because its skin absorption is low, the amount that enters the body from the parent compound is small, and ordinary laundering removes the surface residue. As a mattress-chemistry question, octocrylene alone is minor.
The benzophenone twist
What makes octocrylene worth a page is what it turns into. The molecule slowly degrades into benzophenone — a possible human carcinogen and endocrine disruptor — through a reaction known as a retro-aldol condensation. A 2021 study found benzophenone in octocrylene-containing sunscreens at an average of 39 milligrams per kilogram, rising to 75 after an accelerated-aging protocol, while a product without octocrylene contained none; the authors reported that up to 70% of that benzophenone could be absorbed through skin. Peer-reviewed — Downs et al. 2021 In other words, the worry is not the fresh ingredient but the aged one: benzophenone accumulates in the bottle over time and with heat. Inferred — benzophenone load rises with product age and temperature
Holding both truths at once
The fair reading keeps two findings in view. The EU safety assessment did not cover the benzophenone-degradation question, and the finding has drawn scientific debate; at the same time, the parent compound is well-characterised and low-concern. Regulatory — EU SCCS (scope noted) Peer-reviewed — Norman et al. 2025 The honest synthesis is not "octocrylene is dangerous" and not "there is nothing here" — it is that a generally-safe filter carries an age-and-heat-dependent contaminant, and that the contaminant is the part to manage. Inferred — separating the verdicts on parent compound and degradation product
What the research says
- Octocrylene itself is low-concern. EU SCCS safe to 10%; ~0.33% skin absorption; not genotoxic; no hormone-system effects. Regulatory — EU SCCS Peer-reviewed — Norman et al. 2025
- It degrades to benzophenone. A possible carcinogen/endocrine disruptor that accumulates as product ages; largely skin-absorbable. Peer-reviewed — Downs et al. 2021
- The endocrine worry was reviewed and not confirmed. SCCS found the evidence not conclusive at use levels. Regulatory — EU SCCS
- Sun protection benefit is real. UV filters prevent skin cancer; that is not in dispute. Peer-reviewed — Norman et al. 2025
What helps reduce it
Do not use old or expired sunscreen. Benzophenone accumulates over time, so a fresh product carries far less; replace sunscreen each season. Peer-reviewed — Downs et al. 2021
Store it cool. The degradation is temperature-driven, so keep sunscreen out of hot cars and sunlit bathrooms. Peer-reviewed — Downs et al. 2021
Prefer octocrylene-free or mineral sunscreens if you wish. Zinc oxide and titanium dioxide filters avoid the benzophenone pathway entirely. Inferred — mineral filters do not generate benzophenone
Launder bedding normally. The skin-applied surface residue comes off in the wash. Inferred
What does NOT help
- Skipping sunscreen. The skin-cancer protection from UV filters clearly outweighs the benzophenone concern; the fix is product choice and freshness, not going without. Peer-reviewed — Norman et al. 2025
- Air purifiers. This is a skin-and-fabric residue, not an airborne pollutant. Inferred
Open research questions
- How much benzophenone actually transfers from skin-applied sunscreen onto bedding, and how it compares with the dermal dose. Speculation
- Whether reformulation or stabilisers can suppress octocrylene's retro-aldol degradation in real-world storage. Speculation
Citations
- Downs CA, et al. (2021). Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products. Chemical Research in Toxicology. Benzophenone rose from ~39 to ~75 mg/kg with aging in octocrylene products; up to 70% skin-absorbable. Via Consensus. DOI 10.1021/acs.chemrestox.0c00461 Peer-reviewed
- Norman KG, et al. (2025). Comprehensive review of octocrylene toxicology data and human exposure assessment for personal care products. Critical Reviews in Toxicology. Low skin absorption (0.33%); not genotoxic; no hormone-system effects; margins of safety >100 at ≤10%. Via Consensus. DOI 10.1080/10408444.2025.2593603 Peer-reviewed
- EU Scientific Committee on Consumer Safety. Opinion on Octocrylene (CAS 6197-30-4), SCCS/1627/21 (final, 30–31 March 2021). Safe as a UV filter up to 10% in cosmetics (9% in propellant spray for combined use); endocrine evidence not conclusive; sensitisation negligible. health.ec.europa.eu Regulatory
Frequently asked questions
Why is a sunscreen ingredient in a bedroom atlas?
Because what you put on your skin ends up on your sheets. Octocrylene is a leave-on UV filter in sunscreens, day creams and other cosmetics, and like the other personal-care entries in this Atlas it transfers from skin onto bedding. It is not a mattress ingredient — it is a skin-applied product residue, and the bedroom is simply downstream of your daily routine.
Is octocrylene itself dangerous?
On the weight of the evidence, the parent compound is low-concern. The EU Scientific Committee on Consumer Safety judges octocrylene safe as a UV filter up to 10% in cosmetics, a comprehensive toxicology review found very low skin absorption (about 0.33%) and no genotoxicity or hormone-system effects, and margins of safety were greater than 100. The endocrine-disruption worry that prompted the EU review was examined and found not conclusive at current use levels.
What is the benzophenone concern about?
This is the distinctive issue with octocrylene. The molecule slowly breaks down into benzophenone — a possible carcinogen and endocrine disruptor — through a chemical reaction called a retro-aldol condensation. A 2021 study found benzophenone in octocrylene-containing sunscreens, with concentrations that rose as the products aged, and reported that a large fraction of that benzophenone can be absorbed through skin. The practical implication is straightforward: it is the degradation product, not octocrylene itself, that drives the caution, and it accumulates in old product.
What should I actually do?
Keep using sunscreen — sun protection prevents skin cancer and that benefit is not in dispute. The sensible, low-effort steps are: do not use old or expired sunscreen, since benzophenone accumulates over time; store sunscreen cool rather than in a hot car or bathroom, since the degradation is temperature-driven; and if you prefer, choose octocrylene-free or mineral (zinc/titanium) sunscreens, which avoid the issue entirely. Washing bedding normally removes the skin-applied residue.
Related compounds
Embr is a sleep environment company researching and addressing the chemistry of the bedroom. Research and product development in progress.
Last reviewed 2026-06-27. If you find a factual error, contact us.